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      您現在的位置: 化工網 > 化工基礎數據庫 > 化工字典 > CAS查詢 > CAS 22832-87-7
      22832-87-7 達克寧 結構式圖片
      3D結構圖

      22832-87-7 達克寧

      名稱和標識我要糾錯
      中文別名 英文別名
      Hi-Pick1-[2-(2,4-Dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole NitrateMiconalEcobi-[(2,4-dichlorobenzyl)oxy]phenethyl)imidazoleDaktarVodolBrentanAflorixMicatinmonistat-Derm1-(2,4-Dichloro-&betaFloridMicotef展開∨
      Inchi
      InChI=1S/C18H14Cl4N2O.HNO3/c19-13-2-1-12(16(21)7-13)10-25-18(9-24-6-5-23-11-24)15-4-3-14(20)8-17(15)22;2-1(3)4/h1-8,11,18H,9-10H2;(H,2,3,4)
      CAS InChkey
      MCCACAIVAXEFAL-UHFFFAOYSA-N
      國際化聯命名
      1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole;nitric acid
      物化屬性我要糾錯
      密度:1.451 沸點:555.1 °C at 760 mmHg 閃光點:289.5 °C
    2. PSA:93.10000
    3. LOGP:6.63030
    4. 安全信息我要糾錯
      包裝等級:III 海關編碼:2933990090 危險品運輸編碼:3249 危險類別碼:22-43 安全說明:36/37 危險品標志:Xn
      生產方法及用途我要糾錯
      用途 為廣譜抗霉菌藥,治療深部真菌感染。

      第2部分 危險性概述

      緊急情況概述:

      吞咽有害??赡軐е缕つw過敏反應。

      GHS危險性類別:

      急性經口毒性 類別 4

      皮膚致敏物 類別 1

      標簽要素:
      象形圖:
      警示詞:

      警告

      危險性說明:

      H302 吞咽有害。

      H317 可能導致皮膚過敏反應。

      防范說明:
      • 預防措施:
        • P264 作業后徹底清洗。
        • P270 使用本產品時不要進食、飲 水或吸煙。
        • P261 避免吸入粉塵/煙/氣體/煙霧/蒸氣/噴霧。
        • P272 受沾染的工作服不得帶出工作場地。
        • P280 戴防護手套/穿防護服/戴防 護眼罩/戴防護面具。
      • 事故響應:
        • P301+P312 如誤吞咽: 如感覺不適,呼叫解毒中心/ 醫生
        • P330 漱口。
        • P302+P352 如皮膚沾染: 用水充分清洗。
        • P333+P313 如發生皮膚刺激或皮疹: 求醫/就診。
        • P321 具體治療 ( 見本標簽上的…… )。
        • P362+P364 脫掉沾染的衣服,清洗后方可 重新使用
      • 安全儲存:
      • 廢棄處置:
        • P501 按當地法規處置內裝物/容器。
      物理和化學危險:
      無資料
      健康危害:
      吞咽有害??赡軐е缕つw過敏反應。
      環境危害:
      無資料
      海關數據我要糾錯
      • 中國海關編碼:2933990090
      • 概述:2933290090. 其他結構含非稠合咪唑環的化合物. 增值稅率:17.0%. 退稅率:13.0%. 監管條件:無. 最惠國關稅:6.5%. 普通關稅:20.0%
      • 申報要素:品名, 成分含量, 用途, 烏洛托品請注明外觀, 6-己內酰胺請注明外觀, 簽約日期
      • Summary:2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
      毒性參考我要糾錯
      • 毒性:

        CHEMICAL IDENTIFICATION

        RTECS NUMBER :
        NI4771000
        CHEMICAL NAME :
        Imidazole, 1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)pheneth yl)-, mononitrate
        CAS REGISTRY NUMBER :
        22832-87-7
        LAST UPDATED :
        199504
        DATA ITEMS CITED :
        19
        MOLECULAR FORMULA :
        C18-H14-Cl4-N2-O.H-N-O3
        MOLECULAR WEIGHT :
        479.16
        WISWESSER LINE NOTATION :
        T5N CNJ A1YR CG DG&O1R BG DG &..H..N-O3

        HEALTH HAZARD DATA

        ACUTE TOXICITY DATA

        TYPE OF TEST :
        LD50 - Lethal dose, 50 percent kill
        ROUTE OF EXPOSURE :
        Oral
        SPECIES OBSERVED :
        Rodent - rat
        DOSE/DURATION :
        920 mg/kg
        TOXIC EFFECTS :
        Details of toxic effects not reported other than lethal dose value
        REFERENCE :
        NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,809,1982
        TYPE OF TEST :
        LD50 - Lethal dose, 50 percent kill
        ROUTE OF EXPOSURE :
        Intraperitoneal
        SPECIES OBSERVED :
        Rodent - rat
        DOSE/DURATION :
        1060 mg/kg
        TOXIC EFFECTS :
        Details of toxic effects not reported other than lethal dose value
        REFERENCE :
        NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,809,1982
        TYPE OF TEST :
        LD50 - Lethal dose, 50 percent kill
        ROUTE OF EXPOSURE :
        Subcutaneous
        SPECIES OBSERVED :
        Rodent - rat
        DOSE/DURATION :
        >5 gm/kg
        TOXIC EFFECTS :
        Sense Organs and Special Senses (Eye) - lacrimation Behavioral - ataxia Gastrointestinal - ulceration or bleeding from stomach
        REFERENCE :
        IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 7,353,1976
        TYPE OF TEST :
        LD50 - Lethal dose, 50 percent kill
        ROUTE OF EXPOSURE :
        Intravenous
        SPECIES OBSERVED :
        Rodent - rat
        DOSE/DURATION :
        14700 ug/kg
        TOXIC EFFECTS :
        Details of toxic effects not reported other than lethal dose value
        REFERENCE :
        IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 11,181,1980
        TYPE OF TEST :
        LD50 - Lethal dose, 50 percent kill
        ROUTE OF EXPOSURE :
        Oral
        SPECIES OBSERVED :
        Rodent - mouse
        DOSE/DURATION :
        578 mg/kg
        TOXIC EFFECTS :
        Sense Organs and Special Senses (Eye) - lacrimation Behavioral - ataxia Gastrointestinal - ulceration or bleeding from stomach
        REFERENCE :
        CHTHBK Chemotherapy (Basel). (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY 10003) V.13- 1968- Volume(issue)/page/year: 17(6),392,1972
        TYPE OF TEST :
        LD50 - Lethal dose, 50 percent kill
        ROUTE OF EXPOSURE :
        Intraperitoneal
        SPECIES OBSERVED :
        Rodent - mouse
        DOSE/DURATION :
        480 mg/kg
        TOXIC EFFECTS :
        Details of toxic effects not reported other than lethal dose value
        REFERENCE :
        NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,809,1982
        TYPE OF TEST :
        LD50 - Lethal dose, 50 percent kill
        ROUTE OF EXPOSURE :
        Subcutaneous
        SPECIES OBSERVED :
        Rodent - mouse
        DOSE/DURATION :
        >5 gm/kg
        TOXIC EFFECTS :
        Sense Organs and Special Senses (Eye) - lacrimation Behavioral - ataxia Gastrointestinal - ulceration or bleeding from stomach
        REFERENCE :
        IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 7,353,1976
        TYPE OF TEST :
        LD50 - Lethal dose, 50 percent kill
        ROUTE OF EXPOSURE :
        Intravenous
        SPECIES OBSERVED :
        Rodent - mouse
        DOSE/DURATION :
        28 mg/kg
        TOXIC EFFECTS :
        Details of toxic effects not reported other than lethal dose value
        REFERENCE :
        IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 11,181,1980
        TYPE OF TEST :
        LD50 - Lethal dose, 50 percent kill
        ROUTE OF EXPOSURE :
        Oral
        SPECIES OBSERVED :
        Mammal - dog
        DOSE/DURATION :
        >160 mg/kg
        TOXIC EFFECTS :
        Details of toxic effects not reported other than lethal dose value
        REFERENCE :
        CHTHBK Chemotherapy (Basel). (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY 10003) V.13- 1968- Volume(issue)/page/year: 17(6),392,1972
        TYPE OF TEST :
        LD50 - Lethal dose, 50 percent kill
        ROUTE OF EXPOSURE :
        Oral
        SPECIES OBSERVED :
        Rodent - guinea pig
        DOSE/DURATION :
        276 mg/kg
        TOXIC EFFECTS :
        Details of toxic effects not reported other than lethal dose value
        REFERENCE :
        CHTHBK Chemotherapy (Basel). (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY 10003) V.13- 1968- Volume(issue)/page/year: 17(6),392,1972 ** OTHER MULTIPLE DOSE TOXICITY DATA **
        TYPE OF TEST :
        TDLo - Lowest published toxic dose
        ROUTE OF EXPOSURE :
        Oral
        SPECIES OBSERVED :
        Rodent - rat
        DOSE/DURATION :
        3360 mg/kg/4W-I
        TOXIC EFFECTS :
        Liver - other changes Blood - changes in erythrocyte (RBC) count Related to Chronic Data - changes in ovarian weight
        REFERENCE :
        IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 7,353,1976
        TYPE OF TEST :
        TDLo - Lowest published toxic dose
        ROUTE OF EXPOSURE :
        Oral
        SPECIES OBSERVED :
        Rodent - rat
        DOSE/DURATION :
        15600 mg/kg/26W-I
        TOXIC EFFECTS :
        Liver - changes in liver weight Blood - changes in other cell count (unspecified) Related to Chronic Data - changes in ovarian weight
        REFERENCE :
        IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 7,504,1976
        TYPE OF TEST :
        TDLo - Lowest published toxic dose
        ROUTE OF EXPOSURE :
        Intraperitoneal
        SPECIES OBSERVED :
        Rodent - mouse
        DOSE/DURATION :
        600 mg/kg/6D-I
        TOXIC EFFECTS :
        Liver - other changes Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other hydrolases
        REFERENCE :
        TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 50,269,1988 ** REPRODUCTIVE DATA **
        TYPE OF TEST :
        TDLo - Lowest published toxic dose
        ROUTE OF EXPOSURE :
        Oral
        DOSE :
        1100 mg/kg
        SEX/DURATION :
        female 7-17 day(s) after conception
        TOXIC EFFECTS :
        Reproductive - Specific Developmental Abnormalities - urogenital system Reproductive - Effects on Newborn - live birth index (measured after birth) Reproductive - Effects on Newborn - physical
        REFERENCE :
        IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 7,367,1976
        TYPE OF TEST :
        TDLo - Lowest published toxic dose
        ROUTE OF EXPOSURE :
        Oral
        DOSE :
        330 mg/kg
        SEX/DURATION :
        female 7-17 day(s) after conception
        TOXIC EFFECTS :
        Reproductive - Maternal Effects - parturition
        REFERENCE :
        IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 7,367,1976
        TYPE OF TEST :
        TDLo - Lowest published toxic dose
        ROUTE OF EXPOSURE :
        Oral
        DOSE :
        810 mg/kg
        SEX/DURATION :
        female 17-22 day(s) after conception lactating female 21 day(s) post-birth
        TOXIC EFFECTS :
        Reproductive - Effects on Newborn - stillbirth Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
        REFERENCE :
        IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 7,535,1976
        TYPE OF TEST :
        TDLo - Lowest published toxic dose
        ROUTE OF EXPOSURE :
        Oral
        DOSE :
        270 mg/kg
        SEX/DURATION :
        female 17-22 day(s) after conception lactating female 21 day(s) post-birth
        TOXIC EFFECTS :
        Reproductive - Effects on Newborn - behavioral
        REFERENCE :
        IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 7,535,1976
        TYPE OF TEST :
        TDLo - Lowest published toxic dose
        ROUTE OF EXPOSURE :
        Oral
        DOSE :
        1300 mg/kg
        SEX/DURATION :
        female 6-18 day(s) after conception
        TOXIC EFFECTS :
        Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
        REFERENCE :
        IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 7,377,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6162 No. of Facilities: 393 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 1489 (estimated) No. of Female Employees: 180 (estimated)
      計算化學數據
      • 分子量:479.135g/mol
      • 化合物是否規范:True
      • 準確質量:478.979
      • 同位素質量:476.982
      • 復雜度:441
      • 可旋轉化學鍵數量:6
      • 氫鍵供體數量:1
      • 氫鍵受體計數:5
      • 拓撲極表面積:93.1A^2
      • 重原子數量:29
      • 確定原子立構中心數量:0
      • 不確定原子立構中心數量:1
      • 確定化學鍵立構中心數量:0
      • 不確定化學鍵立構中心數量:0
      • 同位素原子計數:0
      • 共價鍵單元數量:2
      • CACTVS Substructure Key Fingerprint: AAADccB7OAAHAAAAAAAAAAAAAAAAAWAAAAAwYAAAAAAAAAAB0AAAHgIECAAADBbhmiY9kJcMVACh AjBnZQACgC0xF6AJyAAYOoiKbiKBuxmXMAAswAOYqCeQwKAOBAAAAACBAAAIAAAAAQIAAAAAAAAA AA==
      CAS 22832-87-7 近期成交價
      • 價格:¥322.00
        規格:1.0KG
        時間:18/04/27
        收貨地:
        純度:99
      • 價格:¥460.00
        規格:1.0KG
        時間:18/04/02
        收貨地:
        純度: 99%
      • 價格:¥690.00
        規格:1.0G
        時間:18/04/02
        收貨地:
        純度:98
      • 價格:¥782.00
        規格:1.0KG
        時間:18/04/02
        收貨地:
        純度:99
      • 價格:¥92.00
        規格:200.0G
        時間:16/10/21
        收貨地:
        純度:99
      現貨信息
      CAS號:
      現貨熱線:400-8383-985
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